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Stable 5-hydroxymethylcytosine (5hmC) acquisition marks gene activation during chondrogenic differentiation

Regulation of gene expression changes during chondrogenic differentiation by DNA methylation and demethylation is little understood. Methylated cytosines (5mC) are oxidized by the ten-eleven-translocation (TET) proteins to 5-hydroxymethylcytosines (5hmC), 5-formylcytosines (5fC) and 5-carboxylcytosi...

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Bibliografische gegevens
Gepubliceerd in:J Bone Miner Res
Hoofdauteurs: Taylor, Sarah E. B., Li, Ye Henry, Smeriglio, Piera, Rath, Madhusikta, Wong, Wing H., Bhutani, Nidhi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860191/
https://ncbi.nlm.nih.gov/pubmed/26363184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2711
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