Preparation and in vitro release kinetics of ivermectin sustained-release bolus optimized by response surface methodology

Sustained-release formulations of ivermectin (IVM) are useful for controlling parasitic diseases in animals. In this work, an IVM bolus made from microcrystalline cellulose (MCC), starch and low-substituted hydroxypropyl cellulose (LS-HPC) was optimized by response surface methodology. The bolus was...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Ruan, Xiangchun, Gao, Xiuge, Gao, Ying, Peng, Lin, Ji, Hui, Guo, Dawei, Jiang, Shanxiang
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2018
Assuntos:
Veterinary Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074774/
https://ncbi.nlm.nih.gov/pubmed/30083480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5418
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