Preparation and in vitro release kinetics of ivermectin sustained-release bolus optimized by response surface methodology

Sustained-release formulations of ivermectin (IVM) are useful for controlling parasitic diseases in animals. In this work, an IVM bolus made from microcrystalline cellulose (MCC), starch and low-substituted hydroxypropyl cellulose (LS-HPC) was optimized by response surface methodology. The bolus was...

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Bibliographische Detailangaben
Veröffentlicht in:PeerJ
Hauptverfasser: Ruan, Xiangchun, Gao, Xiuge, Gao, Ying, Peng, Lin, Ji, Hui, Guo, Dawei, Jiang, Shanxiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2018
Schlagworte:
Veterinary Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6074774/
https://ncbi.nlm.nih.gov/pubmed/30083480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.5418
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