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Formulation and Optimization of Sustained Release Stavudine Microspheres Using Response Surface Methodology
The aim of the current study was to formulate and optimize the formulation on the basis of in vitro performance of microsphere. A 3(2) full factorial design was employed to study the effect of independent variables, polymer-to-drug ratio (X (1)) and stirring speed (X (2)), on dependent variables, en...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
International Scholarly Research Network
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3263718/ https://ncbi.nlm.nih.gov/pubmed/22389855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2011/627623 |
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