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Formulation development and optimization of sustained release matrix tablet of Itopride HCl by response surface methodology and its evaluation of release kinetics

The objective of this present investigation was to develop and formulate sustained release (SR) matrix tablets of Itopride HCl, by using different polymer combinations and fillers, to optimize by Central Composite Design response surface methodology for different drug release variables and to evalua...

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Bibliographic Details
Main Authors: Bose, Anirbandeep, Wong, Tin Wui, Singh, Navjot
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3744972/
https://ncbi.nlm.nih.gov/pubmed/23960836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsps.2012.03.006
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