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Conformational dynamics and enzyme evolution

Enzymes are dynamic entities, and their dynamic properties are clearly linked to their biological function. It follows that dynamics ought to play an essential role in enzyme evolution. Indeed, a link between conformational diversity and the emergence of new enzyme functionalities has been recognize...

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Detalles Bibliográficos
Publicado en:J R Soc Interface
Main Authors: Petrović, Dušan, Risso, Valeria A., Kamerlin, Shina Caroline Lynn, Sanchez-Ruiz, Jose M.
Formato: Artigo
Idioma:Inglês
Publicado: The Royal Society 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073641/
https://ncbi.nlm.nih.gov/pubmed/30021929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2018.0330
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