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The role of ligand-gated conformational changes in enzyme catalysis

Structural and biochemical studies on diverse enzymes have highlighted the importance of ligand-gated conformational changes in enzyme catalysis, where the intrinsic binding energy of the common phosphoryl group of their substrates is used to drive energetically unfavorable conformational changes in...

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Publicat a:Biochem Soc Trans
Autors principals: Moreira, Cátia, Calixto, Ana Rita, Richard, John P., Kamerlin, Shina Caroline Lynn
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824834/
https://ncbi.nlm.nih.gov/pubmed/31657438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190298
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