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Platinum Complexes Can Bind to Telomeres by Coordination

It is suggested that several compounds, including G-quadruplex ligands, can target telomeres, inducing their uncapping and, ultimately, cell death. However, it has never been demonstrated whether such ligands can bind directly and quantitatively to telomeres. Here, we employed the property of platin...

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Bibliografische gegevens
Gepubliceerd in:Int J Mol Sci
Hoofdauteurs: Saker, Lina, Ali, Samar, Masserot, Caroline, Kellermann, Guillaume, Poupon, Joel, Teulade-Fichou, Marie-Paule, Ségal-Bendirdjian, Evelyne, Bombard, Sophie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6073198/
https://ncbi.nlm.nih.gov/pubmed/29970863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19071951
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