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Identification of human telomerase assembly inhibitors enabled by a novel method to produce hTERT
Telomerase is the enzyme that maintains the length of telomeres. It is minimally constituted of two components: a core reverse transcriptase protein (hTERT) and an RNA (hTR). Despite its significance as an almost universal cancer target, the understanding of the structure of telomerase and the optim...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4551907/ https://ncbi.nlm.nih.gov/pubmed/25958399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv425 |
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