Selectivity of Terpyridine Platinum Anticancer Drugs for G-quadruplex DNA

Guanine-rich DNA can form four-stranded structures called G-quadruplexes (G4s) that can regulate many biological processes. Metal complexes have shown high affinity and selectivity toward the quadruplex structure. Here, we report the comparison of a panel of platinum (II) complexes for quadruplex DN...

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Pubblicato in:Molecules
Autori principali: Morel, Elodie, Beauvineau, Claire, Naud-Martin, Delphine, Landras-Guetta, Corinne, Verga, Daniela, Ghosh, Deepanjan, Achelle, Sylvain, Mahuteau-Betzer, Florence, Bombard, Sophie, Teulade-Fichou, Marie-Paule
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385020/
https://ncbi.nlm.nih.gov/pubmed/30678027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24030404
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