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Subunit-specific NMDAR antagonism dissociates schizophrenia subtype-relevant oscillopathies associated with frontal hypofunction and hippocampal hyperfunction

NMDAR antagonism alters mesolimbic, hippocampal, and cortical function, acutely reproducing the positive, cognitive, and negative symptoms of schizophrenia. These physiological and behavioral effects may depend differentially on NMDAR subtype- and region-specific effects. The dramatic electrophysiol...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Pittman-Polletta, Benjamin, Hu, Kun, Kocsis, Bernat
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072790/
https://ncbi.nlm.nih.gov/pubmed/30072757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29331-8
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