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Abnormal gamma oscillations in NMDAR hypofunction models of schizophrenia

NMDA receptor (NMDAR) hypofunction in Parvalbumin-expressing (PV+) inhibitory neurons (IN) may contribute to symptoms in patients with schizophrenia (SZ). This hypothesis was inspired by studies in humans involving NMDAR antagonists that trigger SZ symptoms. Animal models of SZ using neuropharmacolo...

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Publicat a:Biol Psychiatry
Autors principals: Jadi, Monika P., Behrens, M. Margarita, Sejnowski, Terrence J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720598/
https://ncbi.nlm.nih.gov/pubmed/26281716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.07.005
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