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Subunit-specific NMDAR antagonism dissociates schizophrenia subtype-relevant oscillopathies associated with frontal hypofunction and hippocampal hyperfunction

NMDAR antagonism alters mesolimbic, hippocampal, and cortical function, acutely reproducing the positive, cognitive, and negative symptoms of schizophrenia. These physiological and behavioral effects may depend differentially on NMDAR subtype- and region-specific effects. The dramatic electrophysiol...

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Publicado en:Sci Rep
Autores principales: Pittman-Polletta, Benjamin, Hu, Kun, Kocsis, Bernat
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072790/
https://ncbi.nlm.nih.gov/pubmed/30072757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29331-8
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