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Subunit-specific NMDAR antagonism dissociates schizophrenia subtype-relevant oscillopathies associated with frontal hypofunction and hippocampal hyperfunction

NMDAR antagonism alters mesolimbic, hippocampal, and cortical function, acutely reproducing the positive, cognitive, and negative symptoms of schizophrenia. These physiological and behavioral effects may depend differentially on NMDAR subtype- and region-specific effects. The dramatic electrophysiol...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pittman-Polletta, Benjamin, Hu, Kun, Kocsis, Bernat
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072790/
https://ncbi.nlm.nih.gov/pubmed/30072757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29331-8
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