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Fluorescence anisotropy imaging in drug discovery

Non-invasive measurement of drug-target engagement can provide critical insights in the molecular pharmacology of small molecule drugs. Fluorescence polarization/fluorescence anisotropy measurements are commonly employed in protein/cell screening assays. However, the expansion of such measurements t...

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Bibliografiske detaljer
Udgivet i:Adv Drug Deliv Rev
Main Authors: Vinegoni, Claudio, Feruglio, Paolo Fumene, Gryczynski, Ignacy, Mazitschek, Ralph, Weissleder, Ralph
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072632/
https://ncbi.nlm.nih.gov/pubmed/29410158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2018.01.019
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