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Two-photon Fluorescence Anisotropy Microscopy for Imaging and Direct Measurement of Intracellular Drug Target Engagement
Small molecule therapeutic drugs must reach their intended cellular targets (pharmacokinetics) and engage them to modulate therapeutic effects (pharmacodynamics). These processes are often difficult to measure in vivo due to their complexities and occurrence within single cells. It has been particul...
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| Udgivet i: | IEEE J Sel Top Quantum Electron |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4946648/ https://ncbi.nlm.nih.gov/pubmed/27440991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/JSTQE.2015.2501384 |
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