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In vivo imaging of drug-induced mitochondrial outer membrane permeabilization at single cell resolution

Observing drug responses in the tumor microenvironment in vivo can be technically challenging. As a result, cellular responses to molecularly targeted cancer drugs are often studied in cell culture, which does not accurately represent the behavior of cancer cells growing in vivo. Using high resoluti...

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Detalhes bibliográficos
Main Authors: Earley, Sarah, Vinegoni, Claudio, Dunham, Joshua, Gorbatov, Rostic, Feruglio, Paolo Fumene, Weissleder, Ralph
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3603290/
https://ncbi.nlm.nih.gov/pubmed/22505651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-4096
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