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Genetic status of KRAS influences Transforming Growth Factor-beta (TGF-β) signaling: an insight into Neuropilin-1 (NRP1) mediated tumorigenesis

Oncogenic RAS and deregulated transforming growth factor (TGF)-β signaling have been implicated in several cancers. So far, attempts to target either one of them therapeutically have been futile as both of them are involved in multiple fundamental cellular processes and the normal forms are expresse...

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Foilsithe in:Semin Cancer Biol
Main Authors: Vivekanandhan, Sneha, Mukhopadhyay, Debabrata
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072630/
https://ncbi.nlm.nih.gov/pubmed/29409705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.01.014
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