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Genetic status of KRAS influences Transforming Growth Factor-beta (TGF-β) signaling: an insight into Neuropilin-1 (NRP1) mediated tumorigenesis

Oncogenic RAS and deregulated transforming growth factor (TGF)-β signaling have been implicated in several cancers. So far, attempts to target either one of them therapeutically have been futile as both of them are involved in multiple fundamental cellular processes and the normal forms are expresse...

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Bibliografski detalji
Izdano u:Semin Cancer Biol
Glavni autori: Vivekanandhan, Sneha, Mukhopadhyay, Debabrata
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072630/
https://ncbi.nlm.nih.gov/pubmed/29409705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.01.014
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