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Genetic status of KRAS influences Transforming Growth Factor-beta (TGF-β) signaling: an insight into Neuropilin-1 (NRP1) mediated tumorigenesis
Oncogenic RAS and deregulated transforming growth factor (TGF)-β signaling have been implicated in several cancers. So far, attempts to target either one of them therapeutically have been futile as both of them are involved in multiple fundamental cellular processes and the normal forms are expresse...
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| Veröffentlicht in: | Semin Cancer Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072630/ https://ncbi.nlm.nih.gov/pubmed/29409705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.01.014 |
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