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Triazole–diindolylmethane conjugates as new antitubercular agents: synthesis, bioevaluation, and molecular docking

We describe the synthesis of novel triazole-incorporated diindolylmethanes (DIMs) using a molecular hybridization approach. The in vitro antitubercular activity of the DIMs against Mycobacterium tuberculosis H37Ra (ATCC 25177) was tested in the active and dormant state. Among all the synthesized con...

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Détails bibliographiques
Publié dans:Medchemcomm
Auteurs principaux: Danne, Ashruba B., Choudhari, Amit S., Chakraborty, Shakti, Sarkar, Dhiman, Khedkar, Vijay M., Shingate, Bapurao B.
Format: Artigo
Langue:Inglês
Publié: Royal Society of Chemistry 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072531/
https://ncbi.nlm.nih.gov/pubmed/30108999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00055g
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