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Synthesis and Antitubercular Activity of New Benzo[b]thiophenes

[Image: see text] In vitro and ex vivo efficacies of four series of benzo[b]thiophene-2-carboxylic acid derivatives were studied against Mycobacterium tuberculosis H37Ra (MTB). Benzo[b]thiophenes were also tested in vitro against multidrug resistant Mycobacterium tuberculosis H37Ra (MDR-MTB), and 7b...

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Détails bibliographiques
Publié dans:ACS Med Chem Lett
Auteurs principaux: Mahajan, Pravin S., Nikam, Mukesh D., Nawale, Laxman U., Khedkar, Vijay M., Sarkar, Dhiman, Gill, Charansingh H.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2016
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983740/
https://ncbi.nlm.nih.gov/pubmed/27563398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00077
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