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New Application of 1,2,4-Triazole Derivatives as Antitubercular Agents. Structure, In Vitro Screening and Docking Studies

A series of 1,2,4-triazole derivatives were synthesized and assigned as potential anti-tuberculosis substances. The molecular and crystal structures for the model compounds C1, C12, and C13 were determined using X-ray analysis. The X-ray investigation confirmed the synthesis pathway and the assumed...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Karczmarzyk, Zbigniew, Swatko-Ossor, Marta, Wysocki, Waldemar, Drozd, Monika, Ginalska, Grazyna, Pachuta-Stec, Anna, Pitucha, Monika
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7767103/
https://ncbi.nlm.nih.gov/pubmed/33352814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25246033
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