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Rational design and synthesis of novel phenylsulfonyl-benzamides as anti-prostate cancer agents

Prostate cancer is a major cause of male death worldwide and the identification of new efficient treatments is constantly needed. Different non-steroidal androgen receptor antagonists are approved also in the case of castration-resistant cancer forms. Using a rational approach and molecular modellin...

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Vydáno v:Medchemcomm
Hlavní autoři: Bassetto, Marcella, Ferla, Salvatore, Giancotti, Gilda, Pertusati, Fabrizio, Westwell, Andrew D., Brancale, Andrea, McGuigan, Christopher
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072516/
https://ncbi.nlm.nih.gov/pubmed/30108852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00164a
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