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Design, synthesis and evaluation of new ligustrazine derivatives as potential plasma-stable neuroprotective agents

A series of ligustrazine–phenolic acid esters which exhibited promising neuroprotective activities have previously been reported. Nevertheless, we found that these ester compounds (like T-VA) were not stable in plasma by further in vivo studies. To investigate plasma-stable neuroprotective agents, a...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Medchemcomm
Egile Nagusiak: Zhang, Chenze, Yan, Wenqiang, Zhao, Rui, Xu, Bing, Fang, Xiong, Yan, Mengmeng, Zhang, Yuzhong, Wang, Penglong, Lei, Haimin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Royal Society of Chemistry 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072499/
https://ncbi.nlm.nih.gov/pubmed/30108782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00003k
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