A New Ligustrazine Derivative-Selective Cytotoxicity by Suppression of NF-κB/p65 and COX-2 Expression on Human Hepatoma Cells. Part 3

A new anticancer ligustrazine derivative, 3β-hydroxyolea-12-en-28-oic acid-3,5,6-trimethylpyrazin-2-methylester (T-OA, C(38)H(58)O(3)N(2)), was previously reported. It was synthesized via conjugating hepatoprotective and anticancer ingredients of traditional Chinese medicine. We found that T-OA exer...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zhang, Chenze, Yan, Wenqiang, Li, Bi, Xu, Bing, Gong, Yan, Chu, Fuhao, Zhang, Yuzhong, Yao, Qiuli, Wang, Penglong, Lei, Haimin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519956/
https://ncbi.nlm.nih.gov/pubmed/26193270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160716401
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