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Synthesis and protective effect of new ligustrazine-vanillic acid derivatives against CoCl(2)-induced neurotoxicity in differentiated PC12 cells

Ligustrazine-vanillic acid derivatives had been reported to exhibit promising neuroprotective activities. In our continuous effort to develop new ligustrazine derivatives with neuroprotective effects, we attempted the synthesis of several ligustrazine-vanillic acid amide derivatives and screened the...

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Bibliographic Details
Published in:Chem Cent J
Main Authors: Xu, Bing, Xu, Xin, Zhang, Chenze, Zhang, Yuzhong, Wu, GaoRong, Yan, Mengmeng, Jia, Menglu, Xie, Tianxin, Jia, Xiaohui, Wang, Penglong, Lei, Haimin
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5331027/
https://ncbi.nlm.nih.gov/pubmed/28293281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-017-0250-z
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