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An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge

Molecular dynamics (MD) has become increasingly popular due to the development of hardware and software solutions and the improvement in algorithms, which allowed researchers to scale up calculations in order to speed them up. MD simulations are usually used to address protein folding issues or prot...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Perricone, Ugo, Gulotta, Maria Rita, Lombino, Jessica, Parrino, Barbara, Cascioferro, Stella, Diana, Patrizia, Cirrincione, Girolamo, Padova, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072422/
https://ncbi.nlm.nih.gov/pubmed/30108981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00166a
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