3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1H-Indole Derivatives as New Anticancer Agents in the Treatment of Pancreatic Ductal Adenocarcinoma

A new series of imidazo[2,1-b][1,3,4]thiadiazole derivatives was efficiently synthesized and screened for their in vitro antiproliferative activity on a panel of pancreatic ductal adenocarcinoma (PDAC) cells, including SUIT-2, Capan-1 and Panc-1. Compounds 9c and 9l, showed relevant in vitro antipro...

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Veröffentlicht in:Molecules
Hauptverfasser: Cascioferro, Stella, Li Petri, Giovanna, Parrino, Barbara, El Hassouni, Btissame, Carbone, Daniela, Arizza, Vincenzo, Perricone, Ugo, Padova, Alessandro, Funel, Niccola, Peters, Godefridus J., Cirrincione, Girolamo, Giovannetti, Elisa, Diana, Patrizia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7024338/
https://ncbi.nlm.nih.gov/pubmed/31947550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25020329
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