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An overview of recent molecular dynamics applications as medicinal chemistry tools for the undruggable site challenge

Molecular dynamics (MD) has become increasingly popular due to the development of hardware and software solutions and the improvement in algorithms, which allowed researchers to scale up calculations in order to speed them up. MD simulations are usually used to address protein folding issues or prot...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Medchemcomm
Κύριοι συγγραφείς: Perricone, Ugo, Gulotta, Maria Rita, Lombino, Jessica, Parrino, Barbara, Cascioferro, Stella, Diana, Patrizia, Cirrincione, Girolamo, Padova, Alessandro
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Royal Society of Chemistry 2018
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072422/
https://ncbi.nlm.nih.gov/pubmed/30108981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00166a
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