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New 1,2,4-Oxadiazole Nortopsentin Derivatives with Cytotoxic Activity

New analogs of nortopsentin, a natural 2,4-bis(3′-indolyl)imidazole alkaloid, in which the central imidazole ring of the natural lead was replaced by a 1,2,4-oxadiazole moiety, and in which a 7-azaindole portion substituted the original indole moiety, were efficiently synthesized. Among all derivati...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Cascioferro, Stella, Attanzio, Alessandro, Di Sarno, Veronica, Musella, Simona, Tesoriere, Luisa, Cirrincione, Girolamo, Diana, Patrizia, Parrino, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6357034/
https://ncbi.nlm.nih.gov/pubmed/30626057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17010035
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