DMBA promotes ErbB2-mediated carcinogenesis via ErbB2 and estrogen receptor pathway activation and genomic instability

Environmental factors, including 7,12-dimethylbenz [a]anthracene (DMBA) exposure, and genetic predisposition, including ErbB2 overexpression/amplification, have been demonstrated to increase breast cancer susceptibility. Although DMBA- and ErbB2-mediated breast cancers are well-studied in their resp...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncol Rep
Main Authors: Ma, Zhikun, Kim, Young Mi, Howard, Erin W., Feng, Xiaoshan, Kosanke, Stanley D., Yang, Shihe, Jiang, Yunbo, Parris, Amanda B., Cao, Xia, Li, Shibo, Yang, Xiaohe
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2018
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072406/
https://ncbi.nlm.nih.gov/pubmed/30015966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2018.6545
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