Alkyne–azide cycloaddition analogues of dehydrozingerone as potential anti-prostate cancer inhibitors via the PI3K/Akt/NF-kB pathway

Herein, we report the isolation and synthetic modification of dehydrozingerone (DHZ, 1), a secondary metabolite present in the rhizome of Zingiber officinale. We synthesized O-propargylated dehydrozingerone, which was subsequently coupled by alkyne–azide cycloaddition (3–20) using click chemistry. T...

全面介紹

Na minha lista:
書目詳細資料
發表在:Medchemcomm
Main Authors: Kumar, Chetan, Rasool, Reyaz Ur, Iqra, Zainab, Nalli, Yedukondalu, Dutt, Prabhu, Satti, Naresh K., Sharma, Neha, Gandhi, Sumit G., Goswami, Anindya, Ali, Asif
格式: Artigo
語言:Inglês
出版: Royal Society of Chemistry 2017
主題:
Chemistry
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072283/
https://ncbi.nlm.nih.gov/pubmed/30108729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00267j
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍