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Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner

Telomerase, the end-replication enzyme, is reactivated in malignant cancers to drive cellular immortality. While this distinction makes telomerase an attractive target for anti-cancer therapies, most approaches for inhibiting its activity have been clinically ineffective. As opposed to inhibiting te...

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Zeng, Xuehuo, Hernandez-Sanchez, Wilnelly, Xu, Mengyuan, Whited, Tawna L., Baus, Diane, Zhang, Junran, Berdis, Anthony J., Taylor, Derek J.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6072277/
https://ncbi.nlm.nih.gov/pubmed/29874588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.020
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