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Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner
Telomerase, the end-replication enzyme, is reactivated in malignant cancers to drive cellular immortality. While this distinction makes telomerase an attractive target for anti-cancer therapies, most approaches for inhibiting its activity have been clinically ineffective. As opposed to inhibiting te...
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| Pubblicato in: | Cell Rep |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6072277/ https://ncbi.nlm.nih.gov/pubmed/29874588 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.05.020 |
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