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Expanding the chemotherapeutic potential of an established nucleoside analog with selective targeting of telomerase
The identification of telomerase-mediated telomeric misincorporation of 5-fluoro-2ʹ-deoxyuridine (5-FdU) uncovered a unique approach to telomeric-based therapeutics. Additionally, identification of such a mechanism supports the utility of telomere maintenance mechanisms in guiding therapeutic decisi...
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| Опубликовано в: : | Mol Cell Oncol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Taylor & Francis
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6276856/ https://ncbi.nlm.nih.gov/pubmed/30525101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1536844 |
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