Germline single nucleotide polymorphisms in ERBB3 and BARD1 genes result in a worse relapse free survival response for HER2-positive breast cancer patients treated with adjuvant based docetaxel, carboplatin and trastuzumab (TCH)

Breast cancer is the leading cause of cancer related deaths in women worldwide and is classified into subtypes based on the cancer’s receptor status. Of these subtypes, those expressing the human epidermal growth factor receptor 2 (HER2) receptor were traditionally associated with poor prognosis. Se...

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Vydáno v:PLoS One
Hlavní autoři: Coté, Damien, Eustace, Alex, Toomey, Sinead, Cremona, Mattia, Milewska, Malgorzata, Furney, Simon, Carr, Aoife, Fay, Joanna, Kay, Elaine, Kennedy, Susan, Crown, John, Hennessy, Bryan, Madden, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071997/
https://ncbi.nlm.nih.gov/pubmed/30071039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0200996
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