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Recent advancements in the discovery of protein–protein interaction inhibitors of replication protein A

Due to the relatively high rate of DNA damage that can occur during cell cycle progression, the DNA damage response (DDR) pathway is critical for the survival of eukaryotic cells. Replication protein A (RPA) is an essential cell cycle checkpoint protein that mediates the initiation of the DDR by bin...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Patrone, James D., Waterson, Alex G., Fesik, Stephen W.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071986/
https://ncbi.nlm.nih.gov/pubmed/30108742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6md00460a
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