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Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides

A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides. The required building blocks were conveniently accessible from cysteine and could be applied in a solid phase peptide synthesis protoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Medchemcomm
Hauptverfasser: Silva Nigenda, Ezequiel, Postma, Tobias M., Hezwani, Mohammed, Pirvan, Alin, Gannon, Susan, Smith, Carol-Anne, Riehle, Mathis, Liskamp, Rob M. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071932/
https://ncbi.nlm.nih.gov/pubmed/30108987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00113h
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