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Achieving enhanced cell penetration of short conformationally constrained peptides through amphiphilicity tuning

Due to their enhanced stability and cell permeability, cyclic cell-penetrating peptides have been widely used as delivery vectors for transporting cell-impermeable cargos into cells. In this study, we synthesized a panel of conformationally constrained peptides with either α-helix or β-hairpin confo...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Tian, Yuan, Zeng, Xiangze, Li, Jingxu, Jiang, Yanhong, Zhao, Hui, Wang, Dongyuan, Huang, Xuhui, Li, Zigang
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848794/
https://ncbi.nlm.nih.gov/pubmed/29568420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03614k
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