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Achieving enhanced cell penetration of short conformationally constrained peptides through amphiphilicity tuning

Due to their enhanced stability and cell permeability, cyclic cell-penetrating peptides have been widely used as delivery vectors for transporting cell-impermeable cargos into cells. In this study, we synthesized a panel of conformationally constrained peptides with either α-helix or β-hairpin confo...

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Bibliografske podrobnosti
izdano v:Chem Sci
Main Authors: Tian, Yuan, Zeng, Xiangze, Li, Jingxu, Jiang, Yanhong, Zhao, Hui, Wang, Dongyuan, Huang, Xuhui, Li, Zigang
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848794/
https://ncbi.nlm.nih.gov/pubmed/29568420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03614k
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