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Bim regulates the survival and suppressive capability of CD8(+) FOXP3(+) regulatory T cells during murine GVHD

CD8(+) Foxp3(+) T cells (Tregs) are a potent regulatory population whose functional and ontological similarities to CD4(+) Fox3(+) T cells have not been well delineated. Using an experimental model of graft-versus-host disease (GVHD), we observed that CD8(+) Tregs were significantly less potent than...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Agle, Kimberle, Vincent, Benjamin G., Piper, Clint, Belle, Ludovic, Zhou, Vivian, Shlomchik, Warren, Serody, Jonathan S., Drobyski, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071561/
https://ncbi.nlm.nih.gov/pubmed/29769260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-09-807156
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