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Host interleukin 6 production regulates inflammation but not tryptophan metabolism in the brain during murine GVHD

Graft-versus-host disease (GVHD) induces pathological damage in peripheral target organs leading to well-characterized, organ-specific clinical manifestations. Patients with GVHD, however, can also have behavioral alterations that affect overall cognitive function, but the extent to which GVHD alter...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Belle, Ludovic, Zhou, Vivian, Stuhr, Kara L., Beatka, Margaret, Siebers, Emily M., Knight, Jennifer M., Lawlor, Michael W., Weaver, Casey, Hashizume, Misato, Hillard, Cecilia J., Drobyski, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518565/
https://ncbi.nlm.nih.gov/pubmed/28724796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.93726
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