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The Roles of Interleukin-6 in the Pathogenesis of Rheumatoid Arthritis
Several clinical studies have demonstrated that the humanized anti-interleukin-6 (IL-6) receptor antibody tocilizumab (TCZ) improves clinical symptoms and prevents progression of joint destruction in rheumatoid arthritis (RA). However, the precise mechanism by which IL-6 blockade leads to the improv...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Hindawi Publishing Corporation
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3199948/ https://ncbi.nlm.nih.gov/pubmed/22046525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/765624 |
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