Berberine ameliorates blockade of autophagic flux in the liver by regulating cholesterol metabolism and inhibiting COX2-prostaglandin synthesis

Excessive cholesterol contributes to the development of cardiovascular diseases. Berberine (BBR) has been reported to regulate cholesterol homeostasis. Here, we found that BBR could ameliorate the hepatic autophagic flux blockade caused by cholesterol overloading. The underlying mechanism included l...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Sun, Haidong, Liu, Qian, Hu, Hai, Jiang, Yisheng, Shao, Wentao, Wang, Qihan, Jiang, Zhaoyan, Gu, Aihua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070517/
https://ncbi.nlm.nih.gov/pubmed/30068904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0890-5
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker