Editor’s Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity

Chiral polychlorinated biphenyl (PCB) congeners have been implicated by laboratory and epidemiological studies in PCB developmental neurotoxicity. These congeners are metabolized by cytochrome P450 (P450) enzymes to potentially neurotoxic hydroxylated metabolites (OH-PCBs). The present study explore...

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Vydáno v:Toxicol Sci
Hlavní autoři: Kania-Korwel, Izabela, Lukasiewicz, Tracy, Barnhart, Christopher D., Stamou, Marianna, Chung, Haeun, Kelly, Kevin M., Bandiera, Stelvio, Lein, Pamela J., Lehmler, Hans-Joachim
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
Disposition of Chiral Pcb Congeners
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070089/
https://ncbi.nlm.nih.gov/pubmed/28431184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx071
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