Editor’s Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity

Chiral polychlorinated biphenyl (PCB) congeners have been implicated by laboratory and epidemiological studies in PCB developmental neurotoxicity. These congeners are metabolized by cytochrome P450 (P450) enzymes to potentially neurotoxic hydroxylated metabolites (OH-PCBs). The present study explore...

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Udgivet i:Toxicol Sci
Main Authors: Kania-Korwel, Izabela, Lukasiewicz, Tracy, Barnhart, Christopher D., Stamou, Marianna, Chung, Haeun, Kelly, Kevin M., Bandiera, Stelvio, Lein, Pamela J., Lehmler, Hans-Joachim
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Disposition of Chiral Pcb Congeners
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070089/
https://ncbi.nlm.nih.gov/pubmed/28431184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx071
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