Editor’s Highlight: Congener-Specific Disposition of Chiral Polychlorinated Biphenyls in Lactating Mice and Their Offspring: Implications for PCB Developmental Neurotoxicity

Chiral polychlorinated biphenyl (PCB) congeners have been implicated by laboratory and epidemiological studies in PCB developmental neurotoxicity. These congeners are metabolized by cytochrome P450 (P450) enzymes to potentially neurotoxic hydroxylated metabolites (OH-PCBs). The present study explore...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Kania-Korwel, Izabela, Lukasiewicz, Tracy, Barnhart, Christopher D., Stamou, Marianna, Chung, Haeun, Kelly, Kevin M., Bandiera, Stelvio, Lein, Pamela J., Lehmler, Hans-Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Disposition of Chiral Pcb Congeners
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6070089/
https://ncbi.nlm.nih.gov/pubmed/28431184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfx071
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