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RNA binding proteins co-localize with small tau inclusions in tauopathy

The development of insoluble, intracellular neurofibrillary tangles composed of the microtubule-associated protein tau is a defining feature of tauopathies, including Alzheimer’s disease (AD). Accumulating evidence suggests that tau pathology co-localizes with RNA binding proteins (RBPs) that are kn...

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Veröffentlicht in:Acta Neuropathol Commun
Hauptverfasser: Maziuk, Brandon F., Apicco, Daniel J., Cruz, Anna Lourdes, Jiang, Lulu, Ash, Peter E. A., da Rocha, Edroaldo Lummertz, Zhang, Cheng, Yu, Wai Haung, Leszyk, John, Abisambra, Jose F., Li, Hu, Wolozin, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069705/
https://ncbi.nlm.nih.gov/pubmed/30068389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0574-5
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