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The Influenza B Virus Hemagglutinin Head Domain Is Less Tolerant to Transposon Mutagenesis than That of the Influenza A Virus

Influenza A and B viruses can continuously evade humoral immune responses by developing mutations in the globular head of the hemagglutinin (HA) that prevent antibody binding. However, the influenza B virus HA over time displays less antigenic variation despite being functionally and structurally si...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Fulton, Benjamin O., Sun, Weina, Heaton, Nicholas S., Palese, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069205/
https://ncbi.nlm.nih.gov/pubmed/29899093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00754-18
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